Dr.Subash Gupta

Dr.Subash Gupta, ( Liver Transplantation, Apollo & Artemis )

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Fellowships / Memberships / Work Experiences

Born in Asansol, West Bengal, Dr. Subash Gupta was awarded the National talent Scholarship and in 1981, he was selected for admission to All India Institute of Medical Sciences, New Delhi. An outstanding medical graduate, he was selected for training in general surgery under Prof. T. K. Chattopadhay. During his surgical training in AIIMS, his thesis on perioperative chemotherapy for breast carcinoma was considered as original work and led to the award of the degree of MS.

With a strong interest in liver surgery, he chose to work under Prof. Samiran Nundy in the newly created Department of Surgical Gastroenterology in AIIMS. During his stay there, he contributed to the development of National Medical Journal of India. His groundwork for the Calcutta meeting on Brain stem death and Organ transplantation subsequently led to the passage of Transplant of Human Organ Act by the parliament. His experimental work on liver transplantation greatly contributed to development of liver transplantation in India. His work on proximal lienorenal shunts in patients of extrahepatic obstruction was published in the Annals of Surgery and it helped define the management of these children with recurrent upper gastrointestinal bleeding.

He was then offered a position in Queen Elizabeth Medical Centre in Birmingham. The Q.E. as it is popularly called is a leading centre of liver transplant activity in Europe attracting doctors from all over the world. He studied the pharmacokinetics of microemulsified cyclosporine in liver transplant recipients and showed that its absorption was independent of bile flow. He was then appointed as a Senior Clinical Fellow in St. James’s University Hospital in Leeds where he performed over 300 transplant operations. His research interests led to development of techniques to prevent hepatic artery thrombosis and bile leak in liver transplant recipients. This work was presented in the Dublin meeting of British Transplant Society in 1997. The first living related small bowel transplant in the world was performed while he was there.

Although he was offered a permanent position in St. James’s University Hospital and in Baylor Transplant Institute in Dallas, he decided to return to India where liver transplant activity was in its infancy at that time. In 1998, he began work in Sir Ganga Ram Hospital where he performed the first cadaveric liver transplant of that hospital. His work there led to the formation of a world class transplant centre in India where over 500 liver transplant operations have been done. He is credited with many firsts while working in Delhi as detailed below.

1. Introduction of HTK preservative solution to solve the cold chain problem with UW solution in India.

2. Introduction of middle vein retrieval in donor graft to improve patient outcome in India

3. The development of middle vein clamp test to determine extent of anterior sector congestion. This test eliminates the need for complex computer model and contributed to reducing costs in liver transplantation.

4. The elimination of veno-venous bypass in liver transplantation in India

5. The successful transplant of Hepatitis B patients without the use of expensive immunoglobulins.

6. The successful transplant of the youngest child in India with liver failure

7. The successful transplant of an international patient from across the border with fulminant hepatic failure.

8. The first auxiliary partial orthotopic liver transplant for a child with fulminant hepatic failure.

9. The first successful fast tracking of a transplanted patient to the ward without postoperative stay in the ward.

10.The first living related transplant for portal biliopathy using a venous conduit in the world.

11.The first living related liver transplant for a HIV patient with hepatitis B induced liver failure on HARRT therapy.

Having established the Sir Ganga Ram liver transplant centre, he was inducted to rejuvenate the older centre in Indraprastha Apollo Hospitals. Since 2007, the new team at Indraprastha Apollo has conducted over 350 liver transplant operations and over 300 complex GI surgeries.

His expertise in Liver transplantation has brought India in to the world map as a country of advanced medical care. He has transplanted over 100 patients from Pakistan alone. His patients have come from all parts of the world including developed countries like the US.

The University of Queensland, Australia where he is an honorary Associate Professor of Surgery, has recognized his contribution in the field of transplantation.

In recognition of his extensive experience in liver transplantation, he has been appointed as Senior Consultant in the Institute of Liver and Biliary Sciences in New Delhi.

He has been appointed as Professor of Liver Transplantation in the Institute of Post Graduate medical Education and Research, Kolkata

List of publications

1. Institute of Liver and Biliary Sciences, New Delhi

2. Post Graduate of Medicine, Kolkata

3. Masood Hospital, Lahore, Pakistan

4. Lakeshore Hospital, Kochi

5. Apollo Hospitals, Chennai

6. Birdem Hospital, Dhaka, Bangladesh

7. Jupiter Hospital, Thane

8. Apollo Hospitals, Ahmedabad

9. Apollo Gleneagles, Kolkata

The University of Queensland, Australia where he is an honorary Associate Professor of Surgery, has recognized his contribution in the field of transplantation.

In recognition of his extensive experience in liver transplantation, he has been appointed as Senior Consultant in the Institute of Liver and Biliary Sciences in New Delhi.

He has been appointed as Professor of Liver Transplantation in the Institute of Post Graduate medical Education and Research, Kolkata

List of publications

1: Singhal A, Verma M, Goyal N, Vij V, Wadhawan M, Gupta S. Peroneal neuropathy following liver transplantation: possible predisposing factors and outcome. Exp Clin Transplant. 2009 Dec; 7(4):252-5.

2: Verma V, Gupta S, Soin AS, Nundy S. Does the presence of jaundice and/or a lump in a patient with gall bladder cancer mean that the lesion is not resectable? Dig Surg. 2009; 26(4):306-11

3: Kohli V, Wadhawan M, Gupta S, Roy V. Post transplant complex inferior venacava balloon dilatation after hepatic vein stenting. Cardiovascular Intervent Radiol. 2010 Feb; 33(1):205-8.

4: Singhal A, Srivastava A, Goyal N, Vij V, Wadhawan M, Bera M, Gupta S. Successful living donor liver transplant in a child with Abernethy malformation with biliary atresia, ventricular septal defect and intrapulmonary shunting. Pediatr Transplant. 2009 Dec;13(8):1041-7

5: Marwah S, Khan MM, Chaudhary A, Gupta S, Negi SS, Soin A, Nundy S. Two hundred and forty-one consecutive liver resections: an experience from India. HPB (Oxford). 2007;9(1):29-36.

6: Singhal D, Goyal N, Gupta S, Nundy S. Surgery for obscure lowergastrointestinal bleeding in India. Dig Dis Sci. 2007 Jan;52(1):282-6.

7: Singhal D, Kakodkar R, Soin AS, Gupta S, Nundy S. Sinistral portalhypertension. A case report. JOP. 2006 Nov 10;7(6):670-3.

8: Prasad AS, Gupta S, Kohli V, Pande GK, Sahni P, Nundy S. Proximal splenorenal shunts for extrahepatic portal venous obstruction in children. Ann Surg. 1994 Feb;219(2):193-6.

9: Somashekar U, Gupta S, Soin A, Nundy S. Functional outcome and quality of life following restorative proctocolectomy for ulcerative colitis in Indians. Int J Colorectal Dis. 2010 Aug;25(8):967-73.

10: Singhal D, Goyal N, Gupta S, Soin AS, Nundy S. Isolated loop pancreatic remnant drainage following pancreaticoduodenal resection. Hepatogastroenterology 2008 Mar-Apr;55(82-83):677-80.

11: Singhal D, Goyal N, Soin AS, Gupta S, Nundy S. What are the essential components of a transabdominal devascularization procedure for bleeding esophageal varices? World J Surg. 2007 Apr;31(4):861-2; author reply 863-4

12: Goyal N, Singhal D, Gupta S, Soin AS, Nundy S. Transabdominal gastroesophageal devascularization without transection for bleeding varices: results and indicators of prognosis. J Gastroenterol Hepatol. 2007 Jan;22(1):47-50.

13: Singhal D, Goyal N, Gupta S, Nundy S. Surgery for obscure lowergastrointestinal bleeding in India. Dig Dis Sci. 2007 Jan;52(1):282-6.

14: Singhal D, Vasdev N, Soin A, Gupta S, Nundy S. Distinguishing between periampullary carcinoids and carcinomas-is this possible preoperatively? Indian J Gastroenterol. 2006 Jul-Aug;25(4):206-7.

15: Singhal D, Vasdev N, Soin A, Gupta S, Nundy S. Distinguishing between periampullary carcinoids and carcinomas-is this possible preoperatively? Indian J Gastroenterol. 2006 Jul-Aug;25(4):206-7.

16: Kakodkar R, Gupta S, Nundy S. Complicated colonic diverticulosis: surgical perspective from an Indian Centre. Trop Gastroenterol. 2005 Jul-Sep;26(3):152-5.

17: Kakodkar R, Gupta S, Nundy S. Complicated colonic diverticulosis: surgical perspective from an Indian Centre. Trop Gastroenterol. 2005 Jul-Sep;26(3):152-5.

18: Kanagasundaram NS, Fletcher S, Gupta S, Davison AM. Acute small-bowel obstruction following mesenteric perforation by CAPD catheter. Nephrol DialTransplant. 1997 Mar;12(3):599-600.

19: Fletcher S, Gupta S, Carmichael P, Allsopp L, Lodge JP, Newstead CG. Oliguria in a renal graft: the role of ureteric catheterization. Nephrol Dial Transplant. 1996 Oct;11(10):2083-4.

20. Gupta S. Attitudes to liver transplantation in India. Natl Med J India. 1993 Jul-Aug; 6(4):194.

21: Gupta S, Soin AS, Gupta S, Sharma LK, Sepsis after Ivalon sponge rectopexy: an unusual case, Aust N Z J Surg; 1991, 61: 469-71

22: Generalized peritonitis in India-the tropical spectrum

Sharma L, Gupta S, Soin AS, Sikora S, Kapoor V.. Jpn J Surg. 1991,21:272-7.

23: Pilonidal disease of the umbilicus-a report of two cases.

Gupta S, Sikora S, Singh M, Sharma L. Jpn J Surg. 1990,20:590-2.

24: Bilateral angiosarcoma of the breast: an overview.

Kumar A, Gupta S, Chopra P, Sharma LK. Aust N Z J Surg. 1990,60:341-5

Gupta S, Sikora SS, Gupta R, Singh MK, Chattopadhyay TK. Jpn J Surg. 1989,19:229-31.

25: Presacral neurilemoma (schwannoma)-report of a rare case.

Gupta S, Sikora SS, Gupta R, Singh MK, Chattopadhyay TK. Jpn J Surg. 1989,19:229-31.

26: The management of extensive corrosive esophageal strictures: do not dilate and procrastinate. Chattopadhyay TK, Kapoor VK, Gupta S. Jpn J Surg. 1989,19:171-6.

27: Liver transplantation, an Indian perspective

Gupta S, Bhalla VP, Nundy S. Liver transplantation, an Indian perspective, Ind J Int Med, 1992, 2:227-31

Contributions to Books

1. First National Consensus report on liver transplant and cadaveric organ donation. 2003

Arora A,Gupta S, Soin AS, Saigal S,

2. Brain stem death and organ transplantation in India, New Delhi,

Pande GK, PK, Gupta S, Sahni P. the Natl Med J India, 1990

3. Ethics in liver transplantation

Gupta S, Nundy S., In Kaul HK, Arora MK, Jayalakshmi TS(eds) Recent advances in intensive care, New Delhi: Research society of Anaesthesiology and Allied Sciences, 1991; 102-5

4. Consensus Conference on Liver Transplant in India

Gupta S, Arora A, Saigal S:, publishers, Sir Ganga Ram Hospital.

5. Liver Transplantation

Gupta S, Chapter on Liver Transplantation: Textbook of Surgical Gastroenterology,Vol II,795-806, Editors Haribhakti and others.

6. Text Book of API, (in press), Liver transplantation in India

Subash Gupta and Ajay Kumar

7. Perspectives in organ transplantation

Bhalla VP, Gupta S, Nundy S. Public funding of organ transplantation, In Kapoor VK, Ghosh PK, Bhandari M, Agarwal SS(eds), New Delhi, B. I. Churchill Livingstone, 1993

8. Surgical management of portal hypertension in the tropics.

Recent advances in gastroenterology, Gupta S, Kohli VK, Nundy S. (eds) Goonaratne and D’silva, Ceylon Medical Journal, 1992

Lectures and Oration

He has delivered many lectures both in national and international meetings, a list too exhaustive to list here.

 

Apollo & Artemis Hospital

Email : [email protected]